A provincial governor and former Major League Baseball pitcher Octavio Dotel were among the victims. Dotel, 51, died on the way to hospital after being pulled from the debris.
The incident happened in the early hours of Tuesday at a concert by popular merengue singer Rubby Pérez at the Jet Set nightclub. He was reported among those trapped in the rubble.
Hundreds of people were inside the venue and some 400 rescuers are still searching for survivors. There are fears the death toll will rise further.
BBC